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Nightclubs

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Substance

450 Fremont St, Las Vegas, NV

Substance

Map

Tickets & Reservations

Substance Hours & Information

Nightclub at the Neonopolis in Downtown Las Vegas.

Hours: Friday & Saturday | 10pm - 3am

Type: Nightclub

Ages: 21 and older

Location: Downtown (Neonopolis)

Additional Nightlife Options at Downtown

Glitter Gulch Tiki

Raised By Wolves

The Laundry Room

All Nightlife Offers at Downtown

Bin 702: $5 Pints, $7 Wines + $20 Bottle Specials (Daily 3pm-6pm)

Cat's Meow: 2-for-1 Well Drinks & Beers (Daily 5pm-8pm)

F The Bar: $7 Beers, Cocktails & Margaritas (All-Day)

Oak & Ivy: Happy Hour (Weekdays 3pm-6pm)

Raised By Wolves: $30 Open Bar Party (Thursday-Sunday)

VIEW ALL VEGAS NIGHTLIFE OPTIONS

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